Gene description for TSG101
Gene name tumor susceptibility 101
Gene symbol TSG101
Other names/aliases TSG10
VPS23
Species Homo sapiens
 Experiment description of studies that identified TSG101 in Cervical cancer cells

1
Experiment ID2840
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID2841
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

3
Experiment ID1607
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa - CD63 pull-down fraction
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

4
Experiment ID1611
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa - CD9 pull-down fraction
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

5
Experiment ID1613
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

6
Experiment ID1614
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

7
Experiment ID1614
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

8
Experiment ID1616
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34282141   
OrganismHomo sapiens
Experiment descriptionSpecificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
AuthorsMathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C.
Journal name Nat Commun
Publication year2021
SampleCervical cancer cells
Sample nameHeLa
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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